As a higher-level paraplegic (T3 complete), I suffer from something called "neurogenic bowel" which is how paralysis affects the movement and elimination of food/waste from the body.
Neurogenic bowel can be either "spastic" or "flaccid" and neither is particularly fun to deal with.
Without going into the gory details, we with neurogenic bowel must go to rather great lengths to manage this process and it can mean extended periods spent sitting on a commode or commode wheelchair.
That can lead to everyone's favorite word: hemorrhoids.
Most conventional treatments use things like witch hazel to constrict tissues to stop any bleeding. This has the unwanted side-effect of slowing or even temporarily halting any healing process.
There are more effective, compounded salves for healing these tissues that are available with a prescription. They work by actually relaxing tissue to increase blood flow and healing. They're intended to treat fissures, not hemorrhoids, however.
The compounded salve is both expensive and reliant on the calcium channel blocker nifedipine. Used topically, the risks are likely quite low, but nifedipine is a strong drug with significant side-effects when taken orally. Likely for this reason it is only used externally for the purposes I'm discussing and never in suppository form to treat internal hemorrhoids.
I had many problems over many years dealing with neurogenic bowel, but we eventually developed our CBD meltz and found better relief than the other options discussed here. I think the key is that the CBD seems to relax the tissue like nifedipine, while the carrier ingredients also soothe and protect tissue.
What's more, Meltz are flexible in their use. They can be used like a suppository for internal hemorrhoids, or warmed with fingers and used as an external salve.
Meltz helped me get control and break the cycle of neurogenic bowel and hemorrhoids where conventional treatments did not.